Alexa Fluor® 568 Anti-PD-L1 antibody [28-8] (ab213359) (2024)

Overview

• Product name

  Alexa Fluor® 568 Anti-PD-L1 antibody [28-8]
  See all PD-L1 primary antibodies

• Description

  Alexa Fluor® 568 Rabbit monoclonal [28-8] to PD-L1

• Host species

  Rabbit

• Conjugation

  Alexa Fluor® 568. Ex: 578nm, Em: 603nm

• Tested applications

  Suitable for: ICC/IFmore details

  See Also

  Cut Through the Haze: Can the Latest 3D Imaging Technology Help You Remove Out-of-Focus Blurring?

• Species reactivity

  Reacts with: Human
  

• Immunogen

  Fusion protein. This information is proprietary to Abcam and/or its suppliers.

• Positive control

  • ICC/IF: CHO-PDL1 cells

• General notes

  Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

  Alexa Fluor^® is a registered trademark of Molecular Probes, Inc, a Thermo Fisher Scientific Company. The Alexa Fluor^® dye included in this product is provided under an intellectual property license from Life Technologies Corporation. As this product contains the Alexa Fluor^® dye, the purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). As this product contains the Alexa Fluor^® dye the sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: in manufacturing; (ii) to provide a service, information, or data in return for payment (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are sold for use in research. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

Properties

• Form

  Liquid

• Storage instructions

  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. Store In the Dark.

• Storage buffer

  pH: 7.40
  Preservative: 0.02% Sodium azide
  Constituents: 1% BSA, 30% Glycerol (glycerin, glycerine), PBS

• Concentration information loading...

• Purity

  Protein A purified

• Clonality

  Monoclonal

• Clone number

  28-8

• Isotype

  IgG

• Research areas

  • Immunology
  • Cell Type Markers
  • CD
  • Non-lineage

  • Immunology
  • Immune System Diseases
  • Autoimmune

  • Cancer
  • Tumor immunology
  • Tumor-associated antigens

  • Cancer
  • Tumor biomarkers
  • Tumor antigens

Associated products

• Alternative Versions

  • Anti-PD-L1 antibody [28-8] (ab205921)
  • APC Anti-PD-L1 antibody [28-8] (ab206967)
  • Anti-PD-L1 antibody [28-8] - Low endotoxin, Azide free (ab209889)
  • Alexa Fluor® 488 Anti-PD-L1 antibody [28-8] (ab209959)
  • Alexa Fluor® 647 Anti-PD-L1 antibody [28-8] - Extracellular domain (ab209960)
  • HRP Anti-PD-L1 antibody [28-8] (ab209961)
  • PE Anti-PD-L1 antibody [28-8] (ab209962)
  • Alexa Fluor® 555 Anti-PD-L1 antibody [28-8] (ab213358)
  • Alexa Fluor® 594 Anti-PD-L1 antibody [28-8] (ab213360)
  • FITC Anti-PD-L1 antibody [28-8] (ab224027)
  • Anti-PD-L1 antibody [28-8] - BSA and Azide free (ab228413)

• Isotype control

  • Alexa Fluor® 568 Rabbit IgG, monoclonal [EPR25A] - Isotype Control (ab209613)

• Recombinant Protein

  • Recombinant human PD-L1 protein (Active) (ab167713)

Applications

Target

• Function

  Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

• Tissue specificity

  Highly expressed in the heart, skeletal muscle, placenta and lung. Weakly expressed in the thymus, spleen, kidney and liver. Expressed on activated T- and B-cells, dendritic cells, keratinocytes and monocytes.

• Sequence similarities

  Belongs to the immunoglobulin superfamily. BTN/MOG family.
  Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
  Contains 1 Ig-like V-type (immunoglobulin-like) domain.

• Cellular localization

  Cell membrane and Endomembrane system.

• Information by UniProt

• Database links

  • Entrez Gene: 29126 Human
  • Omim: 605402 Human
  • SwissProt: Q9NZQ7 Human
  • Unigene: 521989 Human

• Alternative names

  • B7 H antibody
  • B7 H1 antibody
  • B7 hom*olog 1 antibody

  see all

Images

Protocols

Datasheets and documents

References (0)